Expresión de búsqueda: CCN INTERCELLULAR SIGNALING PROTEINS 
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Descriptor Inglés:   CCN Intercellular Signaling Proteins 
Descriptor Español:   Proteínas CCN de Señalización Intercelular 
Descriptor Portugués:   Proteínas de Sinalização Intercelular CCN 
Categoría:   D12.644.276.200
D12.776.467.200
D12.776.860.300.200
D23.529.237
Definición Inglés:   A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN. 
Nota Histórica Inglés:   2009 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   53123 
Identificador Único:   D055511 

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